Category: public health

Precision Public Health and Precision Medicine: Two Peas in a Pod

two peas is a pod: first pea has a crowd of figures with one under a magnifying glass- second pod has that individual being examined by a doctor- the pod has DNA on it

  The 2015 US Precision Medicine Initiative promises a new era of biomedical research and its application in health care. The initiative is enabled by rapid advances in biomedical sciences, including genomics and bioinformatics, as well as the progress in communication, information technologies and data science. Targeted cancer therapies are a near term goal for Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and PreventionTags ,

The Success of Precision Medicine Requires a Public Health Perspective

a magifying glass focusing on a figure in red with surrounding figures in blue

The announcement of a new major US Precision Medicine initiative comes more than a decade after the completion of the Human Genome Project, the ambitious project that culminated in sequencing all 3 billion base pairs of our genome. Continuous improvement in the quality of sequencing, dramatic reduction in price, and ongoing advances in multiple sectors Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention1 CommentTags , ,

Family health history is a non-modifiable risk factor—or is it?

a family biking

“I met three different women who had been tested [genetic testing for mutations in the BReast CAncer susceptibility (BRCA) genes] early on, in 1996, when the BRCA test first came out. They told me their family history story of mothers, aunts, uncles, and a dad who suffered from breast or ovarian or related cancers, and Read More >

Posted on by Ridgely Fisk Green,Office of Public Health Genomics, Centers For Disease Control and PreventionTags , ,

Epigenetics and Public Health: Why We Should Pay Attention

Epigenetics and the Agouti Mouse

In September 2014, one of us (MJK) spoke on the topic of epigenetics at the Annual Meeting of the Association for State and Territorial Health Officials (ASTHO). ASTHO is a national organization representing public health agencies in the United States. ASTHO members formulate and influence public health policy and practice. In the midst of a Read More >

Posted on by Muin J. Khoury, Office of Public Health Genomics and Krista Crider, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and PreventionTags , , , ,

Is Genomics Widening the Schism Between Medicine and Public Health?

Grand Canyon

In 2007, we published a paper entitled: “Will genomics heal or widen the schism between medicine and public health?” We explored the long standing split between medicine and public health and how the emergence of genomics and other technologies can affect it. The “schism” was identified by Kerr White in his 1991 book in which Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention1 CommentTags , ,

Public Health Genomics to Save Lives: Available Tools, Actual Examples, Real Success

1. Set Goals by Assessing Data and Available Resources 2. Build Partnerships 3. Conduct Surveillance 4. Provide Info to Policy Makers 5. Make Education Available to the Public 6. Implement Bi-directional Reporting 7. Conduct Surveilance and Assess Results

  Announcing New Tier 1 CDC Public Health Genomics Toolkit and Video Resources Impact… Scalability… Innovation… Evidence-based interventions… Surveillance and evaluation… Partnerships… Timely information to health care, the public, and decision makers… Commitment… These elements are crucial to any public health accomplishment and are recurring themes in 2 new public health genomics resources. Nearly 2 Read More >

Posted on by Scott Bowen, Office of Public Health Genomics, Centers For Disease Control and PreventionTags , , ,

Public Health Genomics Highlights 2013

2013 Highlights with DNA string in the background

At the end of each year, we read about top lists of major events, accomplishments, and milestones. These lists are produced by journal editors, institutions and opinion leaders.  CDC is no exception. In December 2013, CDC published its top 5 accomplishments for 2013, which include the Tips from former smokers campaign, outbreak investigations featuring pathogen Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and PreventionTags , ,

Public Health Genomics in Action: Reducing Morbidity and Mortality from Familial Hypercholesterolemia

Discussion Panel at the Familial Hypercholesterolemia Summit

In September, 2013, I participated in the International Familial Hypercholesterolemia (FH) Summit  in Annapolis, Maryland. The event was sponsored by the FH Foundation, a patient-centered organization formed in 2011 to raise awareness about the condition and to develop actions for saving lives of patients and families with FH.  The meeting brought together, from the US Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and PreventionTags , , ,

Why We Can’t Wait: A Public Health Approach to Health Disparities in Genomic Medicine

six circles surrounding a circle including this text: Ensuring Effective and Responsible Use of Genomic Medicine to Improve Population Health. Circle 1 text: Community. Circle 2 text: Health Care Delivery System. Circle 3 text: Employers and Business. Circle 4 text: The Media. Circle 5 text: Academia. Circle 6 text: Governmental Public Health Infrastucture

In May 2013, I attended and presented at the “Why We Can’t Wait Conference to Eliminate Health Disparities in Genomic Medicine.”  The conference was organized by the University of Miami and Stanford University, with attendees and speakers from academia, consumer organizations, government agencies, public health, clinical practice, and the private sector. A key rationale for Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and PreventionTags , , ,

A Public Health Genomic State-by-State Clickable Map: Accelerating Implementation of Genomics Applications to Improve Population Health

US Map

In recent years, public health programs in several states have used innovative approaches to implement evidence-based genomic testing recommendations in an effort to improve health outcomes for people at increased hereditary risk for breast, ovarian, colorectal and other cancers.  For example, the Michigan Department of Community Health [PDF 1.04 MB] has partnered with payers in Read More >

Posted on by Karen Greendale, MA, CGC, McKing Consulting, Contractor for the Office of Public Health Genomics, Centers for Disease Control and Prevention1 CommentTags , , , , , , ,